(Update: In April of 2017 there was an article posted about this company, so as of May 2017 it is unsure if this company has gone under.) First off, to sign up and become an affiliate of the company you might do a double or triple or quadruple take at the startup cost (which is almost 4 figures). However, you do get to truly set up your own business, because you can set the price on all the products you sell. If you have that business talent to make consumers buy the products (which are legit btw) you can certainly make that start-up cost back in no time. This company has also been achieving some high praise by being the recipient of many awards (including a growth award from the Direct Selling Association).
If you insist on trying one of these MLM offers, the least you can do is look for proper business registration with BBB, toll free number, and proper address (no Post Office box). Also, you will need lots of family and friends to make it work. As a final step, check the MLM materials for one or more of these "red flags" that are associated with the worst of the offerings: